KPNB1 Antikörper

Produktnummer ABIN7239089

Produktdetails anti-KPNB1 Antikörper

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human KPNB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KPNB1

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Andere Bezeichnung: KPNB1 (KPNB1 Produkte)

Synonyme: Afu1g15720 antikoerper, AO090005001133 antikoerper, imb1 antikoerper, impnb antikoerper, ipo1 antikoerper, ipob antikoerper, ntf97 antikoerper, IMB1 antikoerper, IPO1 antikoerper, IPOB antikoerper, Impnb antikoerper, NTF97 antikoerper, AA409963 antikoerper, importin beta-1 subunit antikoerper, Importin beta-1 subunit antikoerper, karyopherin (importin) beta 1 L homeolog antikoerper, importin beta 1 antikoerper, karyopherin subunit beta 1 antikoerper, karyopherin (importin) beta 1 antikoerper, AFUA_1G15720 antikoerper, AOR_1_1974174 antikoerper, Bm1_57540 antikoerper, PMAA_065830 antikoerper, AFLA_083750 antikoerper, TSTA_085870 antikoerper, BDBG_07509 antikoerper, MCYG_00039 antikoerper, kpnb1.L antikoerper, LOC100533387 antikoerper, KPNB1 antikoerper, Kpnb1 antikoerper

Hintergrund: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.

NCBI Accession: NP_002256

UniProt: Q14974

Pathways: Protein targeting to Nucleus