IPO7 Antikörper

Produktnummer ABIN7239092

Produktdetails anti-IPO7 Antikörper

Target: IPO7 (Importin 7 (IPO7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IPO7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human IPO7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IPO7

Target: IPO7 (Importin 7 (IPO7))

Andere Bezeichnung: IPO7 (IPO7 Produkte)

Synonyme: fb33d09 antikoerper, wu:fb33d09 antikoerper, zgc:66425 antikoerper, zgc:76878 antikoerper, imp7 antikoerper, ranbp7 antikoerper, Imp7 antikoerper, RANBP7 antikoerper, A330055O14Rik antikoerper, C330016G14 antikoerper, Ranbp7 antikoerper, importin 7 antikoerper, importin 7 S homeolog antikoerper, importin-7 antikoerper, karyopherin antikoerper, ipo7 antikoerper, ipo7.S antikoerper, IPO7 antikoerper, CpipJ_CPIJ002096 antikoerper, PTRG_08544 antikoerper, SJAG_03693 antikoerper, NAEGRDRAFT_71372 antikoerper, VDBG_01971 antikoerper, MGYG_08162 antikoerper, Tsp_01943 antikoerper, Tsp_01946 antikoerper, Ipo7 antikoerper

Hintergrund: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Molekulargewicht: 120 kDa

NCBI Accession: NP_006382

UniProt: O95373

Pathways: Protein targeting to Nucleus