ITPR2 Antikörper
-
- Target Alle ITPR2 Antikörper anzeigen
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ITPR2 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), ELISA
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthetic peptide of human ITPR2
- Isotyp
- IgG
- Top Product
- Discover our top product ITPR2 Primärantikörper
-
-
- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
- Andere Bezeichnung
- ITPR2 (ITPR2 Produkte)
- Synonyme
- AI649341 antikoerper, InsP3R-2 antikoerper, InsP3R-5 antikoerper, Ip3r2 antikoerper, Itpr5 antikoerper, insP3R2 antikoerper, IP3R2 antikoerper, inositol 1,4,5-trisphosphate receptor type 2 antikoerper, inositol 1,4,5-triphosphate receptor 2 antikoerper, inositol 1,4,5-trisphosphate receptor, type 2 antikoerper, ITPR2 antikoerper, Itpr2 antikoerper
- Hintergrund
- Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- NCBI Accession
- NP_002214
- UniProt
- Q14571
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
-