SLIT2 Antikörper

Produktnummer ABIN7239467

Produktdetails anti-SLIT2 Antikörper

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human SLIT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SLIT2

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Andere Bezeichnung: SLIT2 (SLIT2 Produkte)

Synonyme: SLIL3 antikoerper, Slit-2 antikoerper, Drad-1 antikoerper, E030015M03Rik antikoerper, E130320P19Rik antikoerper, Slil3 antikoerper, mKIAA4141 antikoerper, Slit antikoerper, slil3 antikoerper, slit-2 antikoerper, slit2-a antikoerper, SLIT2 antikoerper, slit guidance ligand 2 antikoerper, slit homolog 2 (Drosophila) antikoerper, slit guidance ligand 2 S homeolog antikoerper, SLIT2 antikoerper, Slit2 antikoerper, slit2 antikoerper, slit2.S antikoerper

Hintergrund: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

Molekulargewicht: 170 kDa

NCBI Accession: NP_004778

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration