KREV-1 antikoerper, KREV1 antikoerper, RAP1 antikoerper, SMGP21 antikoerper, AI848598 antikoerper, G-22K antikoerper, Krev-1 antikoerper, Rap1 antikoerper, RAP-1A antikoerper, rap 1A antikoerper, wu:fc66g06 antikoerper, zgc:86676 antikoerper, krev-1 antikoerper, krev1 antikoerper, rap1 antikoerper, RAP1A, member of RAS oncogene family antikoerper, RAS-related protein 1a antikoerper, RAP1A, member of RAS oncogene family a antikoerper, RAP1A, member of RAS oncogene family L homeolog antikoerper, RAP1A antikoerper, Rap1a antikoerper, rap1aa antikoerper, rap1a.L antikoerper
Hintergrund
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.