ASCC1 Antikörper

Produktnummer ABIN7240817

Produktdetails anti-ASCC1 Antikörper

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCC1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ASCC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASCC1

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Andere Bezeichnung: ASCC1 (ASCC1 Produkte)

Synonyme: ASC1p50 antikoerper, p50 antikoerper, Asc-1 antikoerper, CGI-18 antikoerper, 1810015P09Rik antikoerper, AI550520 antikoerper, activating signal cointegrator 1 complex subunit 1 antikoerper, ascc1 antikoerper, ASCC1 antikoerper, Ascc1 antikoerper

Hintergrund: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

UniProt: Q8N9N2