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JMJD2D Antikörper

KDM4D Reaktivität: Human, Ratte, Maus ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7002265
  • Target Alle JMJD2D (KDM4D) Antikörper anzeigen
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Reaktivität
    Human, Ratte, Maus
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JMJD2D Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human KDM4D
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Andere Bezeichnung
    KDM4D (KDM4D Produkte)
    Synonyme
    JMJD2D antikoerper, 4932416A15 antikoerper, Jmjd2d antikoerper, KDM4D antikoerper, lysine demethylase 4D antikoerper, lysine-specific demethylase 4D antikoerper, lysine (K)-specific demethylase 4D antikoerper, KDM4D antikoerper, LOC524768 antikoerper, Kdm4d antikoerper, LOC617971 antikoerper, LOC100067461 antikoerper, LOC698455 antikoerper, LOC100514356 antikoerper
    Hintergrund
    JMJD2D (Jumonji domain-containing protein 2D), also known as JHDM3D or KDM4D, is a 520 amino acid protein that belongs to the JHDM3 histone demethylase family. Localized to the nucleus, JMJD2D functions as a histone demethylase that removes specific methyl residues from Histone H3, thereby playing a crucial role in the histone code. JMJD2D binds iron as a cofactor and contains one JMJC domain and one JMJN domain, both of which are thought to exhibit enzymatic activity during chromatin remodeling events. In addition, JMJD2D forms a complex with the ligand-bound form of the androgen receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is associated with prostate cancer, suggesting that, via its ability to upregulate AR, JMJD2D may be involved in carcinogenesis.
    Molekulargewicht
    59 kDa
    UniProt
    Q6B0I6
    Pathways
    Warburg Effekt
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