MCTS1 Antikörper

Produktnummer ABIN7241675

Produktdetails anti-MCTS1 Antikörper

Target: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCTS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human MCTS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:1000, IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MCTS1

Target: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Andere Bezeichnung: MCTS1 (MCTS1 Produkte)

Synonyme: MCT-1 antikoerper, MCT1 antikoerper, MCT1a antikoerper, cb517 antikoerper, zgc:55682 antikoerper, 1500019M23Rik antikoerper, zgc:56242 antikoerper, mcts1 antikoerper, MGC89874 antikoerper, MCTS1 antikoerper, MCT-1A antikoerper, mct-1 antikoerper, mct1 antikoerper, MCT-1B antikoerper, mcts1-a antikoerper, mcts1-b antikoerper, MCTS1, re-initiation and release factor antikoerper, solute carrier family 16 (monocarboxylate transporter), member 1b antikoerper, malignant T cell amplified sequence 1 antikoerper, malignant T-cell amplified sequence 1 antikoerper, solute carrier family 16 member 1 antikoerper, malignant T-cell amplified sequence 1 S homeolog antikoerper, monocarboxylate transporter 1 antikoerper, malignant T-cell amplified sequence 1 L homeolog antikoerper, MCTS1 antikoerper, slc16a1b antikoerper, Mcts1 antikoerper, mcts1 antikoerper, SLC16A1 antikoerper, mcts1.S antikoerper, MCT1 antikoerper, mcts1.L antikoerper

Hintergrund: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

Molekulargewicht: 21 kDa

UniProt: Q9ULC4