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MECP2 Antikörper

MECP2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7241678
  • Target Alle MECP2 Antikörper anzeigen
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Reaktivität
    • 98
    • 39
    • 30
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 97
    • 7
    • 1
    Kaninchen
    Klonalität
    • 98
    • 7
    Polyklonal
    Konjugat
    • 64
    • 9
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MECP2 Antikörper ist unkonjugiert
    Applikation
    • 76
    • 60
    • 32
    • 26
    • 12
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human MECP2
    Isotyp
    IgG
    Top Product
    Discover our top product MECP2 Primärantikörper
  • Applikationshinweise
    WB 1:200-1:1000, IHC 1:100-1:300
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Andere Bezeichnung
    MECP2 (MECP2 Produkte)
    Hintergrund
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development.
    Molekulargewicht
    52 kDa
    UniProt
    P51608
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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