OTB1 antikoerper, OTU1 antikoerper, AI850305 antikoerper, fa19h07 antikoerper, otub1 antikoerper, wu:fa19h07 antikoerper, zgc:92839 antikoerper, MGC131231 antikoerper, fb17f04 antikoerper, otub1l antikoerper, wu:fb17f04 antikoerper, zgc:92685 antikoerper, OTU deubiquitinase, ubiquitin aldehyde binding 1 antikoerper, OTU domain, ubiquitin aldehyde binding 1 antikoerper, OTU deubiquitinase, ubiquitin aldehyde binding 1b antikoerper, OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog antikoerper, similar to HSPC263 antikoerper, OTU deubiquitinase, ubiquitin aldehyde binding 1a antikoerper, OTUB1 antikoerper, Otub1 antikoerper, otub1b antikoerper, otub1.L antikoerper, otub1 antikoerper, RGD1565010 antikoerper, otub1a antikoerper
Hintergrund
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth.