ABI1 Antikörper

Produktnummer ABIN7241930

Produktdetails anti-ABI1 Antikörper

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human ABI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: ABI1 (ABI1 Produkte)

Synonyme: ABI-1 antikoerper, ABLBP4 antikoerper, E3B1 antikoerper, NAP1BP antikoerper, SSH3BP antikoerper, SSH3BP1 antikoerper, NAP1 antikoerper, Ssh3bp1 antikoerper, E3b1 antikoerper, abi1 antikoerper, wu:fc66g09 antikoerper, wu:fk56a10 antikoerper, zgc:73174 antikoerper, MGC84356 antikoerper, ABI1 antikoerper, abi-1 antikoerper, e3b1 antikoerper, nap1bp antikoerper, ssh3bp antikoerper, ssh3bp1 antikoerper, wu:fe48a10 antikoerper, zgc:153534 antikoerper, DKFZp469P1319 antikoerper, abl interactor 1 antikoerper, abl-interactor 1 antikoerper, abl-interactor 1a antikoerper, abl interactor 1 S homeolog antikoerper, abl-interactor 1b antikoerper, Abl-interactor 1 antikoerper, Abl interactor 1 antikoerper, ABI1 antikoerper, Abi1 antikoerper, abi1a antikoerper, abi1.S antikoerper, abi1 antikoerper, abi1b antikoerper, Bm1_44660 antikoerper, LOAG_04356 antikoerper

Hintergrund: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14

Molekulargewicht: 55 kDa

NCBI Accession: NP_005461

UniProt: Q8IZP0

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling