GNRHR Antikörper

Produktnummer ABIN7242191

Produktdetails anti-GNRHR Antikörper

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human GNRHR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:5000, IHC 1:150-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GNRHR

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Andere Bezeichnung: GNRHR (GNRHR Produkte)

Synonyme: GNRHR1 antikoerper, GRHR antikoerper, HH7 antikoerper, LHRHR antikoerper, LRHR antikoerper, GNRHR antikoerper, GH1 antikoerper, Lhrhr antikoerper, GNRHR1/III antikoerper, GNRHR2 antikoerper, xgnrhr antikoerper, gnrhr3/ii antikoerper, gnrh-r antikoerper, gonadotropin releasing hormone receptor antikoerper, gonadotropin-releasing hormone receptor antikoerper, GNRHR antikoerper, Gnrhr antikoerper, gnrhr antikoerper, gnrh-r antikoerper

Hintergrund: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Molekulargewicht: 28 kDa

NCBI Accession: NP_000397

UniProt: P30968