RRAD Antikörper

Produktnummer ABIN7242650

Produktdetails anti-RRAD Antikörper

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAD Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human RRAD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RRAD

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Andere Bezeichnung: RRAD (RRAD Produkte)

Synonyme: ZGC:63471 antikoerper, RRAD antikoerper, RAD antikoerper, RAD1 antikoerper, REM3 antikoerper, Rad antikoerper, RRAD, Ras related glycolysis inhibitor and calcium channel regulator antikoerper, Ras-related associated with diabetes antikoerper, RRAD antikoerper, Rrad antikoerper

Hintergrund: The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.

NCBI Accession: NP_004156

UniProt: P55042