FZD8 Antikörper

Produktnummer ABIN7242782

Produktdetails anti-FZD8 Antikörper

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human FZD8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FZD8

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Andere Bezeichnung: FZD8 (FZD8 Produkte)

Synonyme: FZ-8 antikoerper, hFZ8 antikoerper, FZD8 antikoerper, Fz-8 antikoerper, frizzled8 antikoerper, xfz8 antikoerper, Xfz8 antikoerper, frizzled-8 antikoerper, hfz8 antikoerper, Fz8 antikoerper, fzd8 antikoerper, fz5 antikoerper, fz8a antikoerper, fzc antikoerper, wu:fd02c05 antikoerper, zg05 antikoerper, ZG06 antikoerper, Zfz8b antikoerper, fz6 antikoerper, fz8b antikoerper, fzA antikoerper, ik:tdsubc_1e1 antikoerper, xx:tdsubc_1e1 antikoerper, zfzA antikoerper, frizzled class receptor 8 antikoerper, frizzled class receptor 8 S homeolog antikoerper, frizzled class receptor 8 L homeolog antikoerper, frizzled class receptor 8a antikoerper, frizzled class receptor 8b antikoerper, FZD8 antikoerper, fzd8.S antikoerper, fzd8 antikoerper, Fzd8 antikoerper, fzd8.L antikoerper, fzd8a antikoerper, fzd8b antikoerper

Hintergrund: This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

NCBI Accession: NP_114072

UniProt: Q9H461

Pathways: WNT Signalweg