A2AP antikoerper, AAP antikoerper, ALPHA-2-PI antikoerper, API antikoerper, PLI antikoerper, serpin antikoerper, AI747498 antikoerper, Pli antikoerper, Serpimf2 antikoerper, serpinf2 antikoerper, serpinf2l antikoerper, wu:fd57d08 antikoerper, Dmrs91 antikoerper, Pedf antikoerper, serpin family F member 2 antikoerper, serpin family F member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade F, member 2 antikoerper, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a antikoerper, SERPINF2 antikoerper, Serpinf2 antikoerper, SERPINF1 antikoerper, serpinf2a antikoerper, Serpinf1 antikoerper
Hintergrund
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.