Necdin-Like 2 Antikörper
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- Target Alle Necdin-Like 2 (NDNL2) Antikörper anzeigen
- Necdin-Like 2 (NDNL2)
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Necdin-Like 2 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthetic peptide of human NDNL2
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:1000-1:5000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.4 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Necdin-Like 2 (NDNL2)
- Andere Bezeichnung
- NSMCE3 (NDNL2 Produkte)
- Synonyme
- mage antikoerper, zgc:101850 antikoerper, NDNL2 antikoerper, HCA4 antikoerper, MAGEG1 antikoerper, MAGEL3 antikoerper, NSE3 antikoerper, NSMCE3 antikoerper, 5730494G16Rik antikoerper, AI642138 antikoerper, BB044375 antikoerper, Mageg1 antikoerper, mage-g1 antikoerper, NSE3 homolog, SMC5-SMC6 complex component antikoerper, necdin-like 2 antikoerper, Nsmce3 antikoerper, ndnl2 antikoerper, NDNL2 antikoerper, NSMCE3 antikoerper
- Hintergrund
- The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
- Molekulargewicht
- 34 kDa
- NCBI Accession
- NP_619649
- UniProt
- Q96MG7
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