CCDC2 antikoerper, DKFZp469F1522 antikoerper, 1700029H06Rik antikoerper, Ccdc2 antikoerper, Cmg1 antikoerper, b2b796Clo antikoerper, CMG-1 antikoerper, CMG1 antikoerper, intraflagellar transport protein 74/72 antikoerper, intraflagellar transport 74 antikoerper, intraflagellar transport protein 74 homolog antikoerper, IFT74 antikoerper, ift74 antikoerper, LOC100632007 antikoerper, LOC100649180 antikoerper, Ift74 antikoerper
Hintergrund
Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.