DEAF1 Antikörper

Produktnummer ABIN7243235

Produktdetails anti-DEAF1 Antikörper

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEAF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human DEAF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DEAF1

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Andere Bezeichnung: DEAF1 (DEAF1 Produkte)

Synonyme: AU042387 antikoerper, C230009B13Rik antikoerper, NUDR antikoerper, SPN antikoerper, ZMYND5 antikoerper, MYND5 antikoerper, spn antikoerper, DEAF1 antikoerper, nudr antikoerper, zmynd5 antikoerper, CG8567 antikoerper, DEAF-1 antikoerper, Deaf-1 antikoerper, Dmel\\CG8567 antikoerper, deaf1 antikoerper, l(3)76BDv antikoerper, deformed epidermal autoregulatory factor 1 (Drosophila) antikoerper, DEAF1, transcription factor antikoerper, DEAF1 transcription factor antikoerper, deformed epidermal autoregulatory factor 1 homolog antikoerper, Deformed epidermal autoregulatory factor-1 antikoerper, Deaf1 antikoerper, DEAF1 antikoerper, LOC509260 antikoerper, deaf1 antikoerper, deaf-1 antikoerper

Hintergrund: Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

NCBI Accession: NP_066288

UniProt: O75398

Pathways: Tube Formation