PIG11 antikoerper, Tp53i11 antikoerper, Trp53i11 antikoerper, fi47b03 antikoerper, si:ch211-122k23.2 antikoerper, tp53i11 antikoerper, wu:fi47b03 antikoerper, zgc:153054 antikoerper, TP53I11 antikoerper, trp53i11 antikoerper, zgc:113403 antikoerper, tumor protein p53 inducible protein 11 antikoerper, transformation related protein 53 inducible protein 11 antikoerper, tumor protein p53 inducible protein 11b antikoerper, tumor protein p53 inducible protein 11 L homeolog antikoerper, tumor protein p53 inducible protein 11a antikoerper, TP53I11 antikoerper, Trp53i11 antikoerper, Tp53i11 antikoerper, tp53i11b antikoerper, tp53i11.L antikoerper, tp53i11 antikoerper, tp53i11a antikoerper
Hintergrund
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome.