TTI1 Antikörper

Produktnummer ABIN7244333

Produktdetails anti-TTI1 Antikörper

Target: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTI1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human TTI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-150, ELISA 1:2000-10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TTI1

Target: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Andere Bezeichnung: TTI1 (TTI1 Produkte)

Synonyme: KIAA0406 antikoerper, smg-10 antikoerper, 2610036D13Rik antikoerper, AI449463 antikoerper, RGD1562582 antikoerper, TELO2 interacting protein 1 antikoerper, TTI1 antikoerper, Tti1 antikoerper

Hintergrund: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

NCBI Accession: NP_055472

UniProt: O43156