HIRA Antikörper (AA 251-350) (Biotin)
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- Target Alle HIRA Antikörper anzeigen
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HIRA Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HIRA/DGGR1
- Isotyp
- IgG
- Top Product
- Discover our top product HIRA Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
- Andere Bezeichnung
- HIRA (HIRA Produkte)
- Synonyme
- HIRA antikoerper, wu:fb97b07 antikoerper, wu:fi43b08 antikoerper, si:ch211-188g24.3 antikoerper, AA138857 antikoerper, D16Ertd95e antikoerper, N28177 antikoerper, Tuple1 antikoerper, DGCR1 antikoerper, TUP1 antikoerper, TUPLE1 antikoerper, dgcr1 antikoerper, hira-A antikoerper, tup1 antikoerper, tuple1 antikoerper, homolog of histone chaperone HIRA antikoerper, histone cell cycle regulator antikoerper, histone cell cycle regulator a antikoerper, protein HIRA antikoerper, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antikoerper, HIRA antikoerper, histone cell cycle regulator S homeolog antikoerper, histone chaperone HIRA-like protein antikoerper, Tuple1/HirA antikoerper, HIRA antikoerper, hira antikoerper, LOC100052845 antikoerper, LOC100352472 antikoerper, LOC100407742 antikoerper, LOC100450459 antikoerper, LOC100467668 antikoerper, LOC100581135 antikoerper, LOC486424 antikoerper, Hira antikoerper, LOC732736 antikoerper, hira.S antikoerper
- Hintergrund
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Synonyms: DGCR1, DGGR 1, DGGR1, DiGeorge critical region gene 1, HIR, HIR histone cell cycle regulation defective homolog A, HIRA, HIRA protein, HIRA_HUMAN, Protein HIRA, TUP 1, TUP1, TUP1 like enhancer of split protein 1, TUP1-like enhancer of split protein 1, TUPLE 1, TUPLE1.
Background: The HIRA gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in flies, yeast and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
- Gen-ID
- 7290
- Pathways
- Chromatin Binding
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