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HLA-DRA Antikörper

HLA-DRA Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7244882
  • Target Alle HLA-DRA Antikörper anzeigen
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Reaktivität
    • 85
    • 17
    • 10
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 56
    • 43
    • 2
    • 1
    Kaninchen
    Klonalität
    • 58
    • 44
    Polyklonal
    Konjugat
    • 49
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser HLA-DRA Antikörper ist unkonjugiert
    Applikation
    • 46
    • 44
    • 34
    • 29
    • 15
    • 11
    • 10
    • 9
    • 9
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human HLA-DRA
    Isotyp
    IgG
    Top Product
    Discover our top product HLA-DRA Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:100, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Andere Bezeichnung
    HLA-DRA (HLA-DRA Produkte)
    Synonyme
    HLA-DRA1 antikoerper, MLRW antikoerper, DR-alpha antikoerper, HLA-DRA antikoerper, Mamu-DRA1 antikoerper, major histocompatibility complex, class II, DR alpha L homeolog antikoerper, major histocompatibility complex, class II, DR alpha antikoerper, hla-dra.L antikoerper, HLA-DRA antikoerper, MAMU-DRA antikoerper, BOLA-DRA antikoerper
    Hintergrund
    HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
    UniProt
    P01903
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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