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GLUD1 Antikörper

GLUD1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7003577
  • Target Alle GLUD1 Antikörper anzeigen
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Reaktivität
    • 36
    • 17
    • 15
    • 13
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 9
    • 1
    Kaninchen
    Klonalität
    • 41
    • 10
    Polyklonal
    Konjugat
    • 29
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLUD1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 22
    • 19
    • 11
    • 10
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human GLUD1
    Isotyp
    IgG
    Top Product
    Discover our top product GLUD1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.48 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Andere Bezeichnung
    GLUD1 (GLUD1 Produkte)
    Hintergrund
    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 61 kDa

    UniProt
    P00367
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Warburg Effekt
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