Prokineticin Receptor 1 Antikörper

Produktnummer ABIN7245161

Produktdetails anti-Prokineticin Receptor 1 Antikörper

Target: Prokineticin Receptor 1 (PROKR1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prokineticin Receptor 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human PROKR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:40-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Andere Bezeichnung: PROKR1 (PROKR1 Produkte)

Synonyme: EG-VEGFR1 antikoerper, Gpr73 antikoerper, Pkr1 antikoerper, GPR73 antikoerper, GPR73a antikoerper, PKR1 antikoerper, ZAQ antikoerper, PROKR1 antikoerper, prokineticin receptor 1 antikoerper, Prokr1 antikoerper, PROKR1 antikoerper

Hintergrund: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage.PROKR1 (Prokineticin Receptor 1) is a Protein Coding gene. Diseases associated with PROKR1 include Ectopic Pregnancy. Among its related pathways are Peptide ligand-binding receptors and RET signaling. GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide Y receptor activity. An important paralog of this gene is PROKR2.

UniProt: Q8TCW9

Pathways: Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma