G6PC Antikörper

Produktnummer ABIN7245446

Produktdetails anti-G6PC Antikörper

Target: G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser G6PC Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human G6PC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.44 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu G6PC

Target: G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Andere Bezeichnung: G6PC (G6PC Produkte)

Synonyme: AW107337 antikoerper, G6Pase antikoerper, G6pt antikoerper, Glc-6-Pase antikoerper, G6PC1 antikoerper, G6PT antikoerper, GSD1 antikoerper, GSD1a antikoerper, G-6-Pase antikoerper, glucose-6-phosphatase, catalytic antikoerper, glucose-6-phosphatase catalytic subunit antikoerper, glucose-6-phosphatase, catalytic subunit antikoerper, G6pc antikoerper, G6PC antikoerper

Hintergrund: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.

UniProt: P35575

Pathways: Carbohydrate Homeostasis, Cellular Glucan Metabolic Process