KCNN3 Antikörper
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- Target Alle KCNN3 Antikörper anzeigen
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KCNN3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human KCNN3
- Isotyp
- IgG
- Top Product
- Discover our top product KCNN3 Primärantikörper
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- Applikationshinweise
- IHC 1:40-1:200, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.08 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
- Andere Bezeichnung
- KCNN3 (KCNN3 Produkte)
- Synonyme
- KCa2.3 antikoerper, SK3 antikoerper, SKCA3 antikoerper, hSK3 antikoerper, potassium calcium-activated channel subfamily N member 3 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antikoerper, Kcnn3 antikoerper, KCNN3 antikoerper
- Hintergrund
- KCNN3 (Potassium Calcium-Activated Channel Subfamily N Member 3) is a Protein Coding gene. Diseases associated with KCNN3 include Spinocerebellar Ataxia 2 and Bipolar Disorder. Among its related pathways are Insulin secretion and Transmission across Chemical Synapses. GO annotations related to this gene include protein heterodimerization activity and calcium-activated potassium channel activity. An important paralog of this gene is KCNN2.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniProt
- Q9UGI6
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