STRADA Antikörper

Produktnummer ABIN7245662

Produktdetails anti-STRADA Antikörper

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADA Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Andere Bezeichnung: STRADA (STRADA Produkte)

Synonyme: fj99g05 antikoerper, zgc:56109 antikoerper, wu:fj99g05 antikoerper, lyk5 antikoerper, LYK5 antikoerper, NY-BR-96 antikoerper, PMSE antikoerper, STRAD antikoerper, Stlk antikoerper, Lyk5 antikoerper, 2610019A05Rik antikoerper, 6030402H20Rik antikoerper, AI480680 antikoerper, E130112C09Rik antikoerper, STE20-related kinase adaptor alpha antikoerper, ste20-related kinase adaptor alpha antikoerper, STRADA antikoerper, strada antikoerper, Strada antikoerper

Hintergrund: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

UniProt: Q7RTN6

Pathways: AMPK Signaling