ATF6B Antikörper
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- Target Alle ATF6B Antikörper anzeigen
- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATF6B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of human ATF6B
- Isotyp
- IgG
- Top Product
- Discover our top product ATF6B Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
- Andere Bezeichnung
- ATF6B (ATF6B Produkte)
- Synonyme
- CREBL1 antikoerper, CREB-RP antikoerper, G13 antikoerper, AA617266 antikoerper, ATF6beta antikoerper, Creb-rp antikoerper, Crebl1 antikoerper, activating transcription factor 6 beta antikoerper, cyclic AMP-dependent transcription factor ATF-6 beta antikoerper, ATF6B antikoerper, LOC745411 antikoerper, Atf6b antikoerper
- Hintergrund
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 77 kDa
- UniProt
- Q99941
- Pathways
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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