UNC45B Antikörper

Produktnummer ABIN7245968

Produktdetails anti-UNC45B Antikörper

Target: UNC45B (Unc-45 Homolog B (UNC45B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC45B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human UNC45B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UNC45B

Target: UNC45B (Unc-45 Homolog B (UNC45B))

Andere Bezeichnung: UNC45B (UNC45B Produkte)

Synonyme: MGC80931 antikoerper, cmya4 antikoerper, AA445617 antikoerper, Cmya4 antikoerper, D230041A13Rik antikoerper, Unc45 antikoerper, CMYA4 antikoerper, SMUNC45 antikoerper, UNC45 antikoerper, Unc-45B antikoerper, cb393 antikoerper, unc45r antikoerper, wu:fa05a03 antikoerper, wu:fa10f03 antikoerper, wu:fb37f02 antikoerper, wu:fb96f06 antikoerper, wu:fc10f04 antikoerper, unc-45 myosin chaperone B S homeolog antikoerper, unc-45 myosin chaperone B antikoerper, unc45b.S antikoerper, unc45b antikoerper, UNC45B antikoerper, Unc45b antikoerper

Hintergrund: This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 104/95 kDa

UniProt: Q8IWX7