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CASR Antikörper

CASR Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7246118
  • Target Alle CASR Antikörper anzeigen
    CASR (Calcium-Sensing Receptor (CASR))
    Reaktivität
    • 92
    • 51
    • 42
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 91
    • 12
    Kaninchen
    Klonalität
    • 93
    • 10
    Polyklonal
    Konjugat
    • 44
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CASR Antikörper ist unkonjugiert
    Applikation
    • 80
    • 34
    • 23
    • 18
    • 18
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human CASR
    Isotyp
    IgG
    Top Product
    Discover our top product CASR Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CASR (Calcium-Sensing Receptor (CASR))
    Andere Bezeichnung
    CASR (CASR Produkte)
    Synonyme
    CAR antikoerper, EIG8 antikoerper, FHH antikoerper, FIH antikoerper, GPRC2A antikoerper, HHC antikoerper, HHC1 antikoerper, HYPOC1 antikoerper, NSHPT antikoerper, PCAR1 antikoerper, CaR antikoerper, Gprc2a antikoerper, gprc2a antikoerper, xV2R F-1 antikoerper, CASR antikoerper, calcium sensing receptor antikoerper, calcium-sensing receptor antikoerper, calcium-sensing receptor L homeolog antikoerper, CASR antikoerper, Casr antikoerper, casr.L antikoerper
    Hintergrund
    CASR (Calcium Sensing Receptor) is a Protein Coding gene. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant and Hyperparathyroidism, Neonatal. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase binding. An important paralog of this gene is GPRC6A.The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
    UniProt
    P41180
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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