im:7138234 antikoerper, wu:fb12b01 antikoerper, zgc:158151 antikoerper, 4732463H20Rik antikoerper, HPIP antikoerper, pre-B-cell leukemia homeobox interacting protein 1b antikoerper, PBX homeobox interacting protein 1 antikoerper, pre B cell leukemia transcription factor interacting protein 1 antikoerper, pbxip1b antikoerper, PBXIP1 antikoerper, Pbxip1 antikoerper
Hintergrund
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.