MGP Antikörper

Produktnummer ABIN7246430

Produktdetails anti-MGP Antikörper

Target: MGP (Matrix Gla Protein (MGP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MGP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human MGP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:70-1:350, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MGP

Target: MGP (Matrix Gla Protein (MGP))

Andere Bezeichnung: MGP (MGP Produkte)

Synonyme: MGLAP antikoerper, NTI antikoerper, Mglap antikoerper, mgp-A antikoerper, MGP antikoerper, LOC100136434 antikoerper, mgp antikoerper, matrix Gla protein antikoerper, matrix Gla protein L homeolog antikoerper, MGP antikoerper, Mgp antikoerper, mgp.L antikoerper, mgp antikoerper

Hintergrund: Matrix Gla protein (MGP) is is a vitamin K-dependent,extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP),which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS),which is an autosomal recessive disorder characterized by abnormal cartilage calcification,peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.

UniProt: P08493