C8orf4 Antikörper

Produktnummer ABIN7246439

Produktdetails anti-C8orf4 Antikörper

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C8orf4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human C8orf4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:40-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu C8orf4

Target: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Andere Bezeichnung: C8orf4 (C8orf4 Produkte)

Synonyme: TC-1 antikoerper, TC1 antikoerper, 1110065B09Rik antikoerper, AW121743 antikoerper, AW321058 antikoerper, C8ORF4 antikoerper, transcriptional and immune response regulator antikoerper, chromosome 22 open reading frame, human C8orf4 antikoerper, TCIM antikoerper, C22H8ORF4 antikoerper, Tcim antikoerper

Hintergrund: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

UniProt: Q9NR00