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RNF111 Antikörper

RNF111 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7246457
  • Target Alle RNF111 Antikörper anzeigen
    RNF111 (Ring Finger Protein 111 (RNF111))
    Reaktivität
    • 38
    • 32
    • 22
    Human
    Wirt
    • 49
    • 4
    Kaninchen
    Klonalität
    • 51
    • 2
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF111 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human RNF111
    Isotyp
    IgG
    Top Product
    Discover our top product RNF111 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.84 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RNF111 (Ring Finger Protein 111 (RNF111))
    Andere Bezeichnung
    RNF111 (RNF111 Produkte)
    Synonyme
    ARK antikoerper, Arkadia antikoerper, RNF111 antikoerper, rnf111 antikoerper, ark antikoerper, MGC81253 antikoerper, MGC146379 antikoerper, ring finger protein 111 antikoerper, ring finger 111 antikoerper, RNF111 antikoerper, Rnf111 antikoerper, rnf111-b antikoerper, rnf111 antikoerper
    Hintergrund
    The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
    UniProt
    Q6ZNA4
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