IFITM2 Antikörper

Produktnummer ABIN7246760

Produktdetails anti-IFITM2 Antikörper

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFITM2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human IFITM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IFITM2

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Andere Bezeichnung: IFITM2 (IFITM2 Produkte)

Synonyme: 1-8D antikoerper, DSPA2c antikoerper, Ifitm3l antikoerper, fragilis3 antikoerper, mil-3 antikoerper, Ifitml antikoerper, interferon induced transmembrane protein 2 antikoerper, IFITM2 antikoerper, Ifitm2 antikoerper

Hintergrund: IFITM2,also named as 1-8D,belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus (WNV),by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.

UniProt: Q01629