NHP2 Antikörper

Produktnummer ABIN7246787

Produktdetails anti-NHP2 Antikörper

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHP2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human NHP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Andere Bezeichnung: NHP2 (NHP2 Produkte)

Synonyme: DKCB2 antikoerper, NHP2P antikoerper, NOLA2 antikoerper, 2410130M07Rik antikoerper, D11Ertd175e antikoerper, Nola2 antikoerper, NHP2 ribonucleoprotein antikoerper, NHP2 antikoerper, Nhp2 antikoerper

Hintergrund: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 17 kDa

UniProt: Q9NX24

Pathways: Telomere Maintenance