1190009B22 antikoerper, Jr2 antikoerper, [s]3A antikoerper, zgc:101676 antikoerper, zgc:112172 antikoerper, ap1s3 antikoerper, adaptor-related protein complex AP-1, sigma 3 antikoerper, adaptor related protein complex 1 sigma 3 subunit antikoerper, adaptor-related protein complex 1, sigma 3 subunit, b antikoerper, adaptor-related protein complex 1, sigma 3 subunit, a antikoerper, adaptor related protein complex 1 sigma 3 subunit S homeolog antikoerper, Ap1s3 antikoerper, AP1S3 antikoerper, ap1s3b antikoerper, ap1s3a antikoerper, ap1s3.S antikoerper
Hintergrund
This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.