FAM107B Antikörper

Produktnummer ABIN7247411

Produktdetails anti-FAM107B Antikörper

Target: FAM107B (Family with Sequence Similarity 107, Member B (FAM107B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM107B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human FAM107B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:150-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FAM107B

Target: FAM107B (Family with Sequence Similarity 107, Member B (FAM107B))

Andere Bezeichnung: FAM107B (FAM107B Produkte)

Synonyme: C10orf45 antikoerper, 3110001A13Rik antikoerper, AA589595 antikoerper, AA959793 antikoerper, AI132312 antikoerper, family with sequence similarity 107 member B antikoerper, family with sequence similarity 107, member B antikoerper, FAM107B antikoerper, Fam107b antikoerper

Hintergrund: FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

UniProt: Q9H098