GCSH Antikörper

Produktnummer ABIN7247492

Produktdetails anti-GCSH Antikörper

Target: GCSH (Glycine Cleavage System H Protein (GCSH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCSH Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human GCSH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GCSH

Target: GCSH (Glycine Cleavage System H Protein (GCSH))

Andere Bezeichnung: GCSH (GCSH Produkte)

Synonyme: GCE antikoerper, NKH antikoerper, GCSH antikoerper, H-PROTEIN antikoerper, 1100001L02Rik antikoerper, 5730591C18Rik antikoerper, wu:fb14d10 antikoerper, wu:fw84b08 antikoerper, zgc:112535 antikoerper, BA5228 antikoerper, gce antikoerper, gcsh antikoerper, nkh antikoerper, wu:fd56h06 antikoerper, zgc:110557 antikoerper, zgc:92732 antikoerper, glycine cleavage system protein H antikoerper, glycine cleavage system protein H (aminomethyl carrier) antikoerper, glycine cleavage system lipoyl carrier protein GcvH antikoerper, glycine cleavage system H protein antikoerper, glycine cleavage system protein H (aminomethyl carrier), a antikoerper, glycine cleavage system carrier of aminomethyl moiety GcvH antikoerper, leucine rich repeat containing 34 antikoerper, glycine cleavage system protein H (aminomethyl carrier) L homeolog antikoerper, glycine cleavage system protein H (aminomethyl carrier), b antikoerper, GCSH antikoerper, Gcsh antikoerper, gcvH-2 antikoerper, gcvH antikoerper, gcsha antikoerper, LRRC34 antikoerper, gcsh.L antikoerper, gcshb antikoerper

Hintergrund: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

UniProt: P23434