DREAM Antikörper

Produktnummer ABIN7247663

Produktdetails anti-DREAM Antikörper

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DREAM Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human KCNIP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.62 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Andere Bezeichnung: KCNIP3 (KCNIP3 Produkte)

Synonyme: CSEN antikoerper, DREAM antikoerper, KCHIP3 antikoerper, 4933407H12Rik antikoerper, AI413860 antikoerper, Csen antikoerper, KChIP3 antikoerper, R74849 antikoerper, Dream antikoerper, rKChIP3 antikoerper, csen antikoerper, im:7145308 antikoerper, kcnip3 antikoerper, zgc:73306 antikoerper, KCNIP3 antikoerper, potassium voltage-gated channel interacting protein 3 antikoerper, Kv channel-interacting protein 4 antikoerper, calsenilin antikoerper, Kv channel interacting protein 3, calsenilin antikoerper, Kv channel interacting protein 3b, calsenilin antikoerper, KCNIP3 antikoerper, LOC5568664 antikoerper, CpipJ_CPIJ002549 antikoerper, Tsp_05009 antikoerper, Kcnip3 antikoerper, kcnip3b antikoerper, kcnip3 antikoerper

Hintergrund: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

UniProt: Q9Y2W7