HORMAD2 Antikörper

Produktnummer ABIN7247717

Produktdetails anti-HORMAD2 Antikörper

Target: HORMAD2 (HORMA Domain Containing 2 (HORMAD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HORMAD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human HORMAD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HORMAD2

Target: HORMAD2 (HORMA Domain Containing 2 (HORMAD2))

Andere Bezeichnung: HORMAD2 (HORMAD2 Produkte)

Synonyme: 4930529M09Rik antikoerper, HORMA domain containing 2 antikoerper, HORMAD2 antikoerper, Hormad2 antikoerper

Hintergrund: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).

UniProt: Q8N7B1