MAPKAP Kinase 3 Antikörper

Produktnummer ABIN7247837

Produktdetails anti-MAPKAP Kinase 3 Antikörper

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP Kinase 3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human MAPKAPK3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPKAP Kinase 3

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Andere Bezeichnung: MAPKAPK3 (MAPKAPK3 Produkte)

Synonyme: 3PK antikoerper, MAPKAP-K3 antikoerper, MAPKAP3 antikoerper, MAPKAPK-3 antikoerper, MK-3 antikoerper, AI874665 antikoerper, MK3 antikoerper, MapkKapk3 antikoerper, MAPKAPK3 antikoerper, mapkapk3 antikoerper, MGC154360 antikoerper, 3pk antikoerper, mapkap3 antikoerper, zgc:158342 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 S homeolog antikoerper, MAPKAPK3 antikoerper, Mapkapk3 antikoerper, mapkapk3.S antikoerper, mapkapk3 antikoerper

Hintergrund: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.

UniProt: Q16644

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades