SAV1 Antikörper
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- Target Alle SAV1 Antikörper anzeigen
- SAV1 (Salvador Homolog 1 (SAV1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SAV1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of human SAV1
- Isotyp
- IgG
- Top Product
- Discover our top product SAV1 Primärantikörper
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- Applikationshinweise
- IHC 1:100-1:300, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.32 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SAV1 (Salvador Homolog 1 (SAV1))
- Andere Bezeichnung
- SAV1 (SAV1 Produkte)
- Synonyme
- SAV antikoerper, WW45 antikoerper, WWP4 antikoerper, 1700040G09Rik antikoerper, Salv antikoerper, Sav antikoerper, Wwp3 antikoerper, Wwp4 antikoerper, salvador family WW domain containing protein 1 antikoerper, salvador family WW domain containing 1 antikoerper, SAV1 antikoerper, Sav1 antikoerper
- Hintergrund
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
- UniProt
- Q9H4B6
- Pathways
- Stem Cell Maintenance
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