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Cullin 4A Antikörper

CUL4A Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7247885
  • Target Alle Cullin 4A (CUL4A) Antikörper anzeigen
    Cullin 4A (CUL4A)
    Reaktivität
    • 59
    • 27
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 53
    • 6
    Kaninchen
    Klonalität
    • 47
    • 12
    Polyklonal
    Konjugat
    • 31
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Cullin 4A Antikörper ist unkonjugiert
    Applikation
    • 37
    • 24
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human CUL4A
    Isotyp
    IgG
    Top Product
    Discover our top product CUL4A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.62 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Cullin 4A (CUL4A)
    Andere Bezeichnung
    CUL4A (CUL4A Produkte)
    Synonyme
    zgc:64071 antikoerper, CUL4A antikoerper, 2810470J21Rik antikoerper, AW495282 antikoerper, RGD1563853 antikoerper, cullin 4A antikoerper, CUL4A antikoerper, cul4a antikoerper, Cul4a antikoerper
    Hintergrund
    Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83 % identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 88 kDa

    UniProt
    Q13619
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