KEAP1 Antikörper
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- Target Alle KEAP1 Antikörper anzeigen
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KEAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human KEAP1
- Isotyp
- IgG
- Top Product
- Discover our top product KEAP1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.8 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Andere Bezeichnung
- KEAP1 (KEAP1 Produkte)
- Synonyme
- INrf2 antikoerper, KLHL19 antikoerper, INRF2 antikoerper, mKIAA0132 antikoerper, Inrf2 antikoerper, fb36f11 antikoerper, keap1 antikoerper, wu:fb36f11 antikoerper, KEAP1 antikoerper, klhl19 antikoerper, zgc:171654 antikoerper, kelch like ECH associated protein 1 antikoerper, kelch-like ECH-associated protein 1 antikoerper, Kelch-like ECH-associated protein 1 antikoerper, kelch-like ECH-associated protein 1a antikoerper, kelch like ECH associated protein 1 L homeolog antikoerper, kelch-like ECH-associated protein 1b antikoerper, KEAP1 antikoerper, Keap1 antikoerper, keap1a antikoerper, keap1 antikoerper, keap1.L antikoerper, keap1b antikoerper
- Hintergrund
- KEAP1,also named as INRF2,KIAA0132 and KLHL19,is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase,which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2,the ETGE and DLG sites,which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 70 kDa
- UniProt
- Q14145
- Pathways
- Maintenance of Protein Location
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