AI037035 antikoerper, Tb03.48O8.160 antikoerper, zgc:103765 antikoerper, zgc:191605 antikoerper, DKFZp469A2113 antikoerper, COX17 antikoerper, Dopuin antikoerper, COX17, cytochrome c oxidase copper chaperone antikoerper, cytochrome c oxidase assembly protein 17 antikoerper, cytochrome c oxidase copper chaperone antikoerper, COX17 cytochrome c oxidase copper chaperone antikoerper, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) antikoerper, COX17 homolog, cytochrome c oxidase assembly protein (yeast) antikoerper, COX17 cytochrome c oxidase assembly homolog antikoerper, COX17 antikoerper, Cox17 antikoerper, Tc00.1047053508153.994 antikoerper, Tb927.3.2650 antikoerper, PVX_111430 antikoerper, cox17 antikoerper
Hintergrund
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92 % amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.