PIWIL2 Antikörper
Kurzübersicht für PIWIL2 Antikörper (ABIN7004802)
Target
Alle PIWIL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human PIWIL2
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Isotyp
- IgG
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anti-Piwi-Like 2 (PIWIL2) (AA 90-119), (N-Term) antibody
PIWIL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39798 unconjugated
anti-Piwi-Like 2 (PIWIL2) (C-Term) antibodyPIWIL2 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 30-80) antibodyPIWIL2 Reaktivität: Maus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 1-973) antibodyPIWIL2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 287-336) antibodyPIWIL2 Reaktivität: Human, Rind (Kuh), Hund, Schwein, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.7 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PIWIL2 (Piwi-Like 2 (PIWIL2))
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Andere Bezeichnung
- PIWIL2
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Hintergrund
- PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of proliferation in tumors
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UniProt
- Q8TC59
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Pathways
- Stem Cell Maintenance
Target
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