DOK3 Antikörper
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- Target Alle DOK3 Antikörper anzeigen
- DOK3 (Docking Protein 3 (DOK3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DOK3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of human DOK3
- Isotyp
- IgG
- Top Product
- Discover our top product DOK3 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, ELISA 1:1000-1:5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.4 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DOK3 (Docking Protein 3 (DOK3))
- Andere Bezeichnung
- DOK3 (DOK3 Produkte)
- Synonyme
- DOK3 antikoerper, DOKL antikoerper, AI450713 antikoerper, Dokl antikoerper, docking protein 3 antikoerper, DOK3 antikoerper, Dok3 antikoerper
- Hintergrund
- DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
- UniProt
- Q7L591
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