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DOK3 Antikörper

DOK3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7249172
  • Target Alle DOK3 Antikörper anzeigen
    DOK3 (Docking Protein 3 (DOK3))
    Reaktivität
    • 47
    • 29
    • 3
    Human
    Wirt
    • 60
    • 3
    • 1
    Kaninchen
    Klonalität
    • 63
    • 1
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DOK3 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 27
    • 20
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human DOK3
    Isotyp
    IgG
    Top Product
    Discover our top product DOK3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA 1:1000-1:5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DOK3 (Docking Protein 3 (DOK3))
    Andere Bezeichnung
    DOK3 (DOK3 Produkte)
    Synonyme
    DOK3 antikoerper, DOKL antikoerper, AI450713 antikoerper, Dokl antikoerper, docking protein 3 antikoerper, DOK3 antikoerper, Dok3 antikoerper
    Hintergrund
    DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 53 kDa

    UniProt
    Q7L591
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