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ALKBH8 Antikörper

ALKBH8 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7249214
  • Target Alle ALKBH8 Antikörper anzeigen
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Reaktivität
    • 19
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALKBH8 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 10
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Full length fusion protein
    Isotyp
    IgG
    Top Product
    Discover our top product ALKBH8 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Andere Bezeichnung
    ALKBH8 (ALKBH8 Produkte)
    Synonyme
    ABH8 antikoerper, 4930562C03Rik antikoerper, 8030431D03Rik antikoerper, 9430088N01Rik antikoerper, Abh8 antikoerper, alkB homolog 8, tRNA methyltransferase antikoerper, ALKBH8 antikoerper, Alkbh8 antikoerper
    Hintergrund
    ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 75 kDa

    UniProt
    Q96BT7
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