ALKBH8 Antikörper
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- Target Alle ALKBH8 Antikörper anzeigen
- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ALKBH8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Full length fusion protein
- Isotyp
- IgG
- Top Product
- Discover our top product ALKBH8 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.6 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
- Andere Bezeichnung
- ALKBH8 (ALKBH8 Produkte)
- Synonyme
- ABH8 antikoerper, 4930562C03Rik antikoerper, 8030431D03Rik antikoerper, 9430088N01Rik antikoerper, Abh8 antikoerper, alkB homolog 8, tRNA methyltransferase antikoerper, ALKBH8 antikoerper, Alkbh8 antikoerper
- Hintergrund
- ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 75 kDa
- UniProt
- Q96BT7
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