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KIF7 Antikörper

KIF7 Reaktivität: Human, Ratte, Maus IHC (p), IF Wirt: Maus Monoclonal 3I4 unconjugated
Produktnummer ABIN7250092
  • Target Alle KIF7 Antikörper anzeigen
    KIF7 (Kinesin Family Member 7 (KIF7))
    Reaktivität
    • 24
    • 15
    • 15
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 20
    • 4
    Maus
    Klonalität
    • 20
    • 4
    Monoklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIF7 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Produktmerkmale
    Monoclonal Antibody
    Aufreinigung
    Protein A purification
    Immunogen
    Synthetic Peptide
    Klon
    3I4
    Isotyp
    IgG
  • Applikationshinweise
    IHC 1:100-1:300, IF 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KIF7 (Kinesin Family Member 7 (KIF7))
    Andere Bezeichnung
    KIF7 (KIF7 Produkte)
    Synonyme
    KIF7 antikoerper, DDBDRAFT_0204609 antikoerper, DDBDRAFT_0206583 antikoerper, DDB_0204609 antikoerper, DDB_0206583 antikoerper, ACLS antikoerper, HLS2 antikoerper, JBTS12 antikoerper, UNQ340 antikoerper, cos2 antikoerper, costal2 antikoerper, kinesin family member 7 antikoerper, KIF7 antikoerper, kif7 antikoerper, Kif7 antikoerper
    Hintergrund
    This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
    UniProt
    Q2M1P5
    Pathways
    Hedgehog Signalweg
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